Thermo Fisher Scientific CBR4 Polyclonal Antibody
Thermo Fisher Scientific의 CBR4 Polyclonal Antibody는 인간 CBR4 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 버퍼에 보관되며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CBR4. Recombinant protein control fragment (Product # RP-96684) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639330 |
Product Specific Information
Immunogen sequence:
FLVNAAGINR DGLLVRTKTE DMVSQLHTNL LGSMLTCKAA MRTMIQQQGG SIVNVGSIVG LKGNSGQSVY SAS
Sequence identity:
- Mouse: 89%
- Rat: 86%
Target Information
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis.
Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.
The homotetramer has NADPH-dependent quinone reductase activity.
Both homotetramer and heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone, and various other o-quinones and p-quinones (in vitro).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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