Thermo Fisher Scientific PSMB9 Monoclonal Antibody (OTI2B6), TrueMAB
PSMB9 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P) 실험에 적합. 인간, 마우스, 랫, 개 종에 반응. 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21–219 of human PSMB9 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits. Two rings consist of 7 alpha subunits and two rings of 7 beta subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
The immunoproteasome plays a crucial role in processing class I MHC peptides. The PSMB9 gene encodes a member of the proteasome B-type (T1B) family, a 20S core beta subunit located in the class II region of the MHC. Proteolytic processing is required to generate the mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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