
Thermo Fisher Scientific Human GM-CSF, Animal-Free Recombinant Protein, PeproTech
Human GM-CSF 재조합 단백질로, E. coli에서 발현된 동물 유래 성분 없는 고순도 시약입니다. 인간 TF-1 세포 증식 활성 검증 완료. 면역세포 분화 및 염증 연구용으로 적합. -20°C 보관, ELISA 및 기능적 분석에 사용 가능.
- 카탈로그번호
- AF-300-03-xxx (4개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
4개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human GM-CSF, Animal-Free Recombinant Protein, PeproTech
Applications
ELISA
- Tested Dilution: Not specified
- Publications: View 2 publications
Functional Assay
- Assay-dependent
- Publications: View publications
In vitro Assay
- Tested Dilution: Not specified
- Publications: View 93 publications
Miscellaneous PubMed
- Tested Dilution: Not specified
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE |
| Molecular Weight | 14.6 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | ED50 ≤ 0.1 ng/ml (specific activity ≥ 1 x 10^7 units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active protein exists as a homodimer in the extracellular space.
This gene is located in the chromosome region 5q31, associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia. Other genes in this cluster include interleukins 4, 5, and 13.
It plays a role in promoting tissue inflammation. Elevated cytokine levels, including GM-CSF, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.
