Thermo Fisher Scientific SCP2 Polyclonal Antibody
Thermo Fisher Scientific SCP2 폴리클로날 항체는 인간 및 생쥐 시료에서 SCP2 단백질을 검출하기 위한 연구용 항체입니다. Western blot, IHC, ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 세포 내 위치 분석 및 지방 대사 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–322 of human SCP2 (NP_0010070991) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.28 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806499 |
Product Specific Information
Immunogen sequence:
MSSSPWEPAT LRRVFVVGVG MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA CVGYVFGVAE CVLALGFEKM SKGSLGIKFS DRTIPTDKHV DLLINKYGLS AHPVAPQMFG YAGKEHMEKY GTKIEHFAKI GWKNHKHSVN NPYSQFQDEY SLDEVMASKE VFDFLTILQC CPTSDGAAAA ILASEAFVQK YGLQSKAVEI LAQEMMTDLP SSFEEKSIIK MVGFDMSKEA ARKCYEKSGL TPNDIDVIEL HDCFSTNELL TYEALGLCPE GQGATLVDRG DNTYGGKWVI NPSGGLISKG HPLGATGGHS CS
Positive Samples: Mouse liver
Cellular Location: Cytoplasm, Mitochondrion, Peroxisome
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
The proximal promoter encodes the longer SCPx protein, while the distal promoter encodes the shorter SCP2 protein. Both share a common C-terminus.
SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, whereas SCP2 acts as an intracellular lipid transfer protein.
This gene is highly expressed in organs involved in lipid metabolism and may be implicated in Zellweger syndrome, characterized by peroxisome deficiency and impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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