Thermo Fisher Scientific ANO3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ANO3 C-terminal region. Validated for Western blot at 0.2–1.0 µg/mL. High homology across multiple species. Supplied as liquid, 0.5 mg/mL, affinity purified, stored at -20°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human ANO3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688647 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, also known as anoctamins. Mutations in this gene have been associated with autosomal dominant craniocervical dystonia. Cells with these mutations show abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat indicate that the ortholog interacts with and modulates a sodium-activated potassium channel. Deletion of this gene increased pain sensitivity in rat models. Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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