Tango™ GPR35-bla U2OS Cells

Tango™ GPR35-bla U2OS cells contain the human G-protein coupled receptor 35 (GPR35) linked to a TEV protease site and a자세히 알아보기

Tango™ GPR35-bla U2OS cells contain the human G-protein coupled receptor 35 (GPR35) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR35-bla U2OS cells have been functionally validated for Z` factor and EC50 concentrations of Zaprinast. In addition, Tango™ GPR35-bla U2OS cells have been tested for assay performance under variable conditions.

사양

등록 번호NM_005301.2

어세이 입력Cell-based beta-arrestin recruitment

셀 상태Dividing Cells

세포질 후미Native Tail

검출 방법Fluorescence

용도(애플리케이션)FRET

인간 단백질 분류G-Protein Coupled Receptor (GPCR)

개체군 상태Single Cell Clone Origin

제품라인Tango™

수량1 vial

판독End Point

타겟 입력GPR35

세포주U2OS

System TypeTango™

Druggable TargetGPCR

Unit SizeEach