Thermo Fisher Scientific Human LZTR1 Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 14 amino acids near the amino terminus of human LZTR1.
PEP-1016 can be used as a blocking peptide with polyclonal antibody PA5-20902.

Target Information

LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family. The encoded protein has been shown to localize exclusively to the Golgi network, where it may help stabilize the Golgi complex.
Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities, and facial dysmorphism.
LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.