Thermo Fisher Scientific GPR37 Polyclonal Antibody
GPR37 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat에서 반응하며, Protein A로 정제된 고순도 항체. 연구용으로 파킨슨병 관련 단백질 연구에 적합.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GPR37, amino acids 201–300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Parkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s disease, affecting about 1% of people over 65 and 3% over 75. Mutations in the Park2 gene are the most common known cause of Parkinson’s disease. Although the function of Park2 is not fully understood, it may participate in the ubiquitin-mediated proteolytic pathway. Mutations can cause autosomal recessive juvenile parkinsonism. Alternative splicing produces three known isoforms of undetermined function. Panneuronal expression of Parkin substrate Pael-R induces age-dependent degeneration of dopaminergic neurons in Drosophila, while coexpression of Parkin degrades Pael-R and suppresses its toxicity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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