Thermo Fisher Scientific NKG2D Monoclonal Antibody (1D11), FITC
인간 NKG2D(CD314)을 인식하는 FITC 결합 단클론 항체로, NK 및 T세포 분석용으로 적합합니다. Flow Cytometry에 최적화된 형광 특성(Ex/Em 498/517 nm)을 가지며, 액상 형태로 안정적 보관이 가능합니다.
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Applications
- Flow Cytometry (Flow): 4 µL/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D11 |
| Immunogen | NKL cell line |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534540 |
Additional Formats
- Unconjugated (MA5-46196)
- APC (A15725)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of CD314 / NKG2D, a 42 kDa C-type lectin-like activating receptor expressed by NK cells, gamma/delta T cells, and CD8+ T cells.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without prior activation. NK cells regulate humoral and cell-mediated immunity and express several calcium-dependent (C-type) lectins involved in NK cell function regulation.
The NKG2 gene encodes a transmembrane protein with a type II membrane orientation and a C-type lectin domain. The NKG2 gene family is located within the NK complex, which contains several C-type lectin genes preferentially expressed in NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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