Thermo Fisher Scientific Human GSK-3B (GSK3 beta), His Tag Recombinant Protein
Human GSK-3B (GSK3 beta) His-tagged recombinant protein for kinase assay and signaling research. Full-length, purified, unconjugated protein expressed in baculovirus system. Stable at -80°C with 6-month guaranteed storage. For research use only.
- 카테고리
- Protein
- 판매단위
- pk
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Applications
- Kinase Assay (KA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Baculovirus |
| Amino Acid Sequence | Full length |
| Tag | His-tag |
| Molecular Weight | 53.1 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris, pH 7.5, with 150 mM NaCl, 0.01% Triton X-100, 2 mM DTT, 50% glycerol, 0.5 mM EDTA |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; materials can be used directly from original packaging until exhausted.
For larger sizes, reduce freeze/thaw cycles by preparing aliquots (do not prepare aliquots below 20 µL).
Never store kinase diluted.
If properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length
Target Information
GSK3B is a proline-directed serine/threonine kinase involved in:
- Energy metabolism and neuronal development
- Regulation of glucose homeostasis
- Inflammation, ER-stress, mitochondrial dysfunction, and apoptosis pathways
- Wnt/β-catenin signaling (inhibits Wnt signaling by mediating β-catenin degradation)
- Hedgehog, Notch, and insulin signaling pathways
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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