Thermo Fisher Scientific PRUNE2 Polyclonal Antibody
PRUNE2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, ICC/IF에 적합하며 인간 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PRUNE2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 2298–2437). Recombinant protein control fragment (Product #RP-110173). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092204 |
Product Specific Information
Immunogen sequence:
AFDHSFSDAS GLNTSTGTID DMSKLTLSEG HPETPVDGDL GKQDICSSEA SWGDFEYDVM GQNIDEDLLR EPEHFLYGGD PPLEEDSLKQ SLAPYTPPFD LSYLTEPAQS AETIEEAGSP EDESLGCRAA EIVLSALPDR
Antigen sequence identity:
- Mouse: 82%
- Rat: 23%
Target Information
PRUNE2 gene (also named BMCC1) encodes protein prune homolog 2. This gene overlaps with PCA3, one of the most prostate cancer–specific markers. PRUNE2 may play an important role in regulating differentiation, survival, and aggressiveness of tumor cells.
It is highly expressed in the nervous system (brain, cerebellum, spinal cord) and in certain cancer cell lines such as neuroblastoma, rhabdomyosarcoma, melanoma, and osteosarcoma. Expression is low in liver, breast, thyroid, and colon cancer cell lines.
Calculated molecular weight: 340 kDa
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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