Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI3G12), TrueMAB
인간 F13A1 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(Paraffin)에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI3G12), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G12 |
| Immunogen | Full length human recombinant protein of human F13A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits serve as plasma carrier molecules. Platelet factor XIII consists of 2 A subunits identical to those of plasma origin. Upon thrombin cleavage and in the presence of calcium ions, plasma factor XIII dissociates its B subunits to yield the active enzyme, factor XIIIa. This enzyme acts as a transglutaminase to catalyze crosslinking between fibrin molecules, stabilizing the clot. It also crosslinks alpha-2-plasmin inhibitor or fibronectin to fibrin alpha chains. Factor XIII deficiency can cause bleeding tendency, defective wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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