Thermo Fisher Scientific Lamin-A/C Polyclonal Antibody
Rabbit 폴리클로날 항체로 Lamin A/C 단백질 검출에 사용. Western blot과 Immunoprecipitation에 적합. 인간 Lamin A/C 150–200번 잔기 영역을 면역원으로 함. Rat 및 Pig에서도 반응 예측. 연구용으로만 사용.
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Thermo Fisher Scientific Lamin-A/C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human Lamin A/Lamin C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Pig
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. They exist in forms A, B, and C, with Lamins A and C being alternatively spliced products of the LMNA gene.
Mutations in LMNA are associated with several disorders, including:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Charcot-Marie-Tooth disease (CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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