Thermo Fisher Scientific CHP Monoclonal Antibody (S2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

S2

Immunogen

CHP (AAH08373, 1 a.a. approximately 66 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHP1,uniProtId:Q99653-1,ncbiNodeId:9606,antigenRange:1-195,antigenLength:195,antigenImageFileName:H00011261-M02_CHP1_Q99653-1_House_mouse.svg,antigenImageFileNamePDP:H00011261-M02_CHP1_Q99653-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MESHSVTQAG VQWRDLGSLQ PLPPGFKQFS HLSLPSSWDY RRVPPYLGNF CIFSGEGVSP CWPGWS

Target Information

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.