Thermo Fisher Scientific CHRM2 Polyclonal Antibody
CHRM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC(P) 분석에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 단기 보관, 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human mAChR M2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2079967 |
Product Specific Information
PA1-32702 detects CHRM2 from human samples.
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor that functions as a presynaptic autoreceptor inhibiting acetylcholine release. The M2 receptor also mediates smooth muscle contractility. In Alzheimer’s disease, selective loss of M2 subtype receptors occurs in cortical and hippocampal regions. Increased M2 receptor heterozygosity has been associated with depression in women. The M2 receptor is expressed in various brain regions including cerebellum, cerebral cortex, hippocampus, medulla, striatum, thalamus, as well as in lung and prostate.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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