Thermo Fisher Scientific INTS6 Polyclonal Antibody
Human INTS6 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장 버퍼를 사용합니다. 종 특이성은 Human이며, 장기 보관은 -20°C에서 권장됩니다.
- 카탈로그번호
- PA551599
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human INTS6. Recombinant protein control fragment (Product #RP-95937) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642746 |
Product Specific Information
Immunogen sequence:
KYELEPSPLT QFILERKSPQ TCWQVYVSNS AKYSELGHPF GYLKASTALN CVNLFVMPYN YPVLLPLLDD LFKVHKAKPT LKWRQSFESY LKTMPPYYLG PLKKAVRMMG APNLIADSME YGLSYSVISY LKKLSQQAKI ES
- Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.
INTS6 is a DEAD box protein that forms part of a complex interacting with the C-terminus of RNA polymerase II, participating in 3′ end processing of snRNAs.
This gene is a candidate tumor suppressor located in a region of loss of heterozygosity (LOH).
Three transcript variants encoding two different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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