Thermo Fisher Scientific CYB5R3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CYB5R3. Recombinant protein control fragment (Product #RP-91345). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYB5R3,uniProtId:P00387-1,ncbiNodeId:9606,antigenRange:146-290,antigenLength:301,antigenImageFileName:PA5-51601_CYB5R3_P00387-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51601_CYB5R3_P00387-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640299

Product Specific Information

Immunogen sequence: SGLLVYQGKG KFAIRPDKKS NPIIRTVKSV GMIAGGTGIT PMLQVIRAIM KDPDDHTVCH LLFANQTEKD ILLRPELEEL RNKHSARFKL WYTLDRAPEA WDYGQGFVNE EMIRDHLPPP EEEPLVLMCG PPPMIQYACL PNLDH

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

Target Information

CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.