Thermo Fisher Scientific SGMS1 Polyclonal Antibody
Human SGMS1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 최적화됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SGMS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790916 |
Product Specific Information
Immunogen sequence:
ASTMKEVVYW SPKKVADWLL ENAMPEYCEP LEHFTGQDLI NLTQEDFKKP PLCRVSSDNG QRLLDMIETL KMEHHLEAHK NGHANGHLNI GVDIPTPDGS FSIKIKPNGM PNGYRKEMIK IPM
Target Information
A bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG), and the inverse reaction. The reaction direction depends on the relative concentrations of DAG and ceramide as phosphocholine acceptors. The enzyme recognizes the choline head group on the substrate and requires two fatty chains on the choline-P donor molecule for efficient substrate recognition. It may not function strictly as a sphingomyelin synthase. The enzyme is inhibited by bacterial PC-phospholipase C inhibitor D609 and is localized to the Golgi apparatus and Golgi membrane as a multi-pass membrane protein. It is possibly present in brain, heart, kidney, liver, muscle, and stomach tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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