Thermo Fisher Scientific TSH Monoclonal Antibody (3B12D11)

Thermo Fisher Scientific TSH Monoclonal Antibody (3B12D11)

Applications

• ELISA (ELISA)

Tested Dilution: 0.05–0.2 µg/mL
Publications: [References not provided]

Product Specifications

Product Specific Information

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit and a unique beta subunit that confers specificity. Free alpha and beta subunits have essentially no biological activity.

TSH (Thyroid Stimulating Hormone) is secreted from cells in the anterior pituitary and is indispensable for the control of thyroid structure and metabolism. GenScript TSH Antibody (3B12D11), mAb, Mouse is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified TSH from human pituitary.

Target Information

The four human glycoprotein hormones—chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH)—are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, while their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.