Thermo Fisher Scientific CCL23/Myeloid Progenitor Inhibitory Factor 1 Monoclonal Antibody (CCL23/4034)

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 1–2 µg/mL

Peptide Array

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Positive Control: High levels in adult lung, liver, skeletal muscle, and pancreas
• Cellular Location: Secreted

Target Information

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide.
This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils, and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.