Thermo Fisher Scientific AKAP10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AKAP10. Recombinant protein control fragment (Product #RP-102397). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AKAP10,uniProtId:O43572-1,ncbiNodeId:9606,antigenRange:212-341,antigenLength:662,antigenImageFileName:PA5-56007_AKAP10_O43572-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56007_AKAP10_O43572-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637802

Product Specific Information

Immunogen sequence: SAQLFMTHSE GIDLNNRTNS TQNHLLLSQE CDSAHSLRLE MARAGTHQVS METQESSSTL TVASRNSPAS PLKELSGKLM KSIEQDAVNT FTKYISPDAA KPIPITEAMR NDIIARICGE DGQVDPNCFV

Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 80%.

Target Information

The A-kinase anchor proteins are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.