Thermo Fisher Scientific GPR30 Polyclonal Antibody
GPR30 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 사람, 생쥐, 랫트 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. 에스트로겐 수용체 관련 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 307–375 of human GPER1 (NP_0014961) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.84 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804365 |
Product Specific Information
Immunogen sequence:
HIVNLAAFSN SCLNPLIYSF LGETFRDKLR LYIEQKTNLP ALNRFCHAAL KAVIPDSTEQ SDVRFSSAV
Positive Samples:
Mouse brain, Mouse heart, Rat brain
Cellular Location:
Basolateral cell membrane, Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle membrane, Early endosome, Endoplasmic reticulum membrane, Golgi apparatus, Golgi apparatus membrane, Mitochondrion membrane, Multi-pass membrane protein, Nucleus, Recycling endosome, Axon, Cytoskeleton, Dendrite, Dendritic spine membrane, Perinuclear region, Postsynaptic cell membrane, Postsynaptic density, Synapse, Trans-Golgi network
Target Information
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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