Thermo Fisher Scientific ASCC1 Monoclonal Antibody (OTI2D7), TrueMAB
ASCC1 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 유세포분석에 적합합니다. 인간 유래 단백질을 면역원으로 사용하며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D7 |
| Immunogen | Full length human recombinant protein of human ASCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex.
The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors, including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB), and serum response factor (SRF).
The encoded protein contains an N-terminal KH-type RNA-binding motif required for AP-1 transactivation by the ASC-1 complex.
Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.
Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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