Thermo Fisher Scientific Human 4EBP1 Synthetic Peptide
인간 4EBP1 단백질의 C-말단 14개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20135와 함께 차단 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며 PBS 완충액에 0.1% BSA 포함, -20°C에서 보관합니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human 4E-BP1.
PEP-0253 can be used as a blocking peptide with polyclonal antibody PA5-20135.
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. The protein is phosphorylated in response to various signals, including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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