Thermo Fisher Scientific MEL18 Polyclonal Antibody
Thermo Fisher Scientific의 MEL18 Polyclonal Antibody는 인간 MEL18 단백질을 인식하는 염소 유래 다클론 항체로, Western blot 분석에 적합합니다. 0.5 mg/mL 농도의 액상 형태이며, 단기 보관은 4°C, 장기 보관은 -20°C에서 가능합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide KMTVNGAPVPPLT (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1956686 |
Product Specific Information
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX25267-PEP).
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis.
This protein acts as a negative regulator of transcription and has tumor suppressor activity. Expression is detected in various tumor cells but limited in neural organs in normal tissues.
Knockout studies in mice suggest that this protein may negatively regulate cytokines, chemokines, and chemokine receptors, playing an important role in lymphocyte differentiation, migration, and immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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