Thermo Fisher Scientific Human BMP-4, Animal-Free Recombinant Protein, PeproTech
Animal-free recombinant Human BMP-4 protein from Thermo Fisher Scientific for research use only. E. coli-derived, ≥98% purity, endotoxin <0.1 EU/µg. Induces alkaline phosphatase in ATDC-5 cells with ED50 of 5–10 ng/ml. Lyophilized form, stored at -20°C.
- 카탈로그번호
- 4개 옵션
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
4개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human BMP-4, Animal-Free Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publications (25 available)
Miscellaneous PubMed (Misc)
- Refer to publications (3 available)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Amphibian, Human, Mouse, Rat |
| Expression System | E. coli |
| Amino Acid Sequence | MKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR |
| Molecular Weight | 24.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | Induces alkaline phosphatase in ATDC-5 cells (ED50: 5–10 ng/ml) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
- Catalog No. AF-120-05ET-1MG is supplied as 2 × 500 µg (AF-120-05ET-500UG).
- PeproTech’s E. coli-derived BMP-4 is a fully active homodimeric protein consisting of two 107 amino acid subunits corresponding to amino acids 303–408 of the BMP-4 precursor, with an N-terminal Met residue.
- The calculated molecular weight is 24.2 kDa.
- Shipped at ambient temperature.
- For storage, handling, and reconstitution details, refer to the lot-specific Certificate of Analysis.
Target Information
The BMP-4 gene encodes a member of the bone morphogenetic protein family, part of the transforming growth factor-beta superfamily. These proteins are key growth and differentiation factors. BMPs were initially identified by their ability to induce endochondral osteogenesis. BMP-4 plays a crucial role in bone formation and its reduced expression is linked to bone disorders such as Fibrodysplasia Ossificans Progressiva.
Alternative splicing in the 5′ untranslated region produces three variants encoding an identical protein.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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