Thermo Fisher Scientific SAPK4 Polyclonal Antibody
Thermo Fisher Scientific의 SAPK4 Polyclonal Antibody는 Human p38 MAPK delta를 인식하는 Rabbit IgG 항체로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA552465
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SAPK4 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human p38 MAPK delta. Recombinant protein control fragment (Product #RP-89798). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645143 |
Product Specific Information
Immunogen sequence:
KTLFKGKDYL DQLTQILKVT GVPGTEFVQK LNDKAAKSYI QSLPQTPRKD FTQLFPRASP QAADLLEKML ELDVDKRLTA AQALTHPFFE PFRDPEEETE AQQPFDDSLE HEKLTVDEWK QHIYKEIVNF SPIARKDS
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 92%
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces various extracellular signals including cytokine and environmental stress responses. It also regulates keratinocyte differentiation. Activation occurs via phosphorylation by MAP kinase kinases or autophosphorylation triggered by interaction with MAP3K7IP1/TAB1. Substrates include transcription regulators (ATF2, MEF2C, MAX), cell cycle regulator (CDC25B), and tumor suppressor (p53), indicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.