Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI6D3), TrueMAB
인간 APOBR 단백질을 표적으로 하는 Mouse IgG1 단클론 항체입니다. IHC(P)에서 1:150 희석 비율로 사용 가능하며, 고순도 친화 크로마토그래피 정제 제품입니다. PBS/BSA/glycerol 버퍼에 보관되며 연구용으로 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of human APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride-rich lipoproteins (TRL) or to a similar domain of APOB in hypertriglyceridemic very low-density lipoprotein (HTG-VLDL).
This receptor binds and internalizes TRL outside the macrophage context, potentially providing essential lipids to reticuloendothelial cells.
It may also be involved in foam cell formation under elevated TRL and remnant lipoprotein (RLP) conditions.
Mediates rapid, high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro in macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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