Thermo Fisher Scientific Cdc25C Polyclonal Antibody
Human CDC25C 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.63 mg/mL 농도. 세포 주기 조절 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–288 of Human CDC25C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545266 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat
- Predicted reactivity: Chimpanzee (83%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved and plays a key role in cell division regulation. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family. It dephosphorylates cyclin B-bound CDC2 (CDK1), triggering entry into mitosis, and may suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described, though the full-length nature of many remains unknown.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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