Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
Human CTHRC1 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 글리세롤이 포함되어 안정적입니다. 혈관 재형성 및 암 전이 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CTHRC1. Recombinant protein control fragment (Product #RP-107108) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664360 |
Product Specific Information
Immunogen sequence:
QCSWSSLNYGI DLGKIAECTF TKMRSNSALR VLFSGSLRLK CRNACCQRWY FTFNGAECSG PLPI
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein transiently expressed in the arterial wall in response to injury. It contributes to vascular remodeling by inhibiting collagen expression and promoting cell migration. CTHRC1 is highly expressed in multiple human cancers, including pancreatic cancer, where it regulates tumor cell migration and adhesion. Overexpression can serve as a prognostic marker in gastric cancer. Mutations at this locus are associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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