Thermo Fisher Scientific HTR7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:10-1:2,000

-

Flow Cytometry (Flow)

Assay-Dependent

-

Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues 13-28 of rat 5-HT7R. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HTR7,uniProtId:P32305-1,ncbiNodeId:10114,antigenRange:13-28,antigenLength:448,antigenImageFileName:PA1-41122_HTR7_P32305-1_Rabbit.svg,antigenImageFileNamePDP:PA1-41122_HTR7_P32305-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2122687

Product Specific Information

This antibody is predicted to react with porcine samples based on sequence homology.

The immunogen sequence is 93% conserved with canine 5-HT7Ra/b, and 81% conserved with porcine 5-HT7R.

Target Information

5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa. 5-HT7 Receptor has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel. An EST has been isolated from a testis library.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.