Thermo Fisher Scientific HTR7 Polyclonal Antibody
HTR7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, Flow cytometry에 사용 가능. 다양한 종(Dog, Human, Mouse, Rat)에 반응하며, 단백질 G로 정제된 액상형 항체. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:10–1:2,000 | - |
| Flow Cytometry (Flow) | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 13–28 of rat 5-HT7R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2122687 |
Product Specific Information
This antibody is predicted to react with porcine samples based on sequence homology.
The immunogen sequence is 93% conserved with canine 5-HT7Ra/b, and 81% conserved with porcine 5-HT7R.
Target Information
5-HT7 Receptor is a serotonin receptor involved in regulating circadian rhythm and mediating smooth-muscle relaxation in the vasculature and GI tract.
It has been implicated in depression, autism, and other neuropsychiatric disorders.
Three protein isoforms have been documented:
- Isoform a: 445 aa
- Isoform b: 432 aa
- Isoform d: 479 aa
Expression has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel.
An EST has been isolated from a testis library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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