Thermo Fisher Scientific TRIP13 Polyclonal Antibody
TRIP13 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. 인간에 반응하며 Rat과 Pig에서도 예측 반응. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 4°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of Human Thyroid Hormone Receptor Interactor 13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Pig
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate gene expression in a hormone-dependent manner.
TRIP13 (Thyroid Hormone Receptor Interactor 13), also known as 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as various target genes including human papilloma virus type 16 (HPV16) E1.
Unlike most TRIP proteins that function only in the presence of hormones, TRIP13 interacts with TR independently of thyroid hormone.
The association of TRIP13 with HPV16 E1 suggests a potential tumor suppressor role. TRIP13 is a 432-amino-acid protein with two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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