Thermo Fisher Scientific Axiom Caprine Genotyping v2 Array, mini-96 format

Applied Biosystems™ Axiom™ Caprine Genotyping v2 Array, mini-96 format

The Axiom Caprine Genotyping v2 Array is a component of the Axiom Agrigenomics Genotyping solution, where target genomic DNA is prepared and processed on the GeneTitan Multi-Channel instrument.
The automated process includes hybridization of gDNA to this high-throughput microarray followed by staining, washing, imaging, and output of genotyping data for further analysis.

Collaborative Design

This array was designed in collaboration with the International Goat Genome Consortium and the VarGoats Consortium.
It includes single-nucleotide polymorphisms (SNPs) from the Illumina Goat_IGGC_65K_v2 and IMAGE 10K goat chip (more info PDF).
Additionally, the array includes insertions, deletions, and duplications targeted by 1 to 50 probes along with 59,795 SNPs and 265 structural variants.

This array is also available in 384HT format.

Key Features

• Updated design including the original goat SNP panel for compatibility with previous studies
• Innovative approach targeting structural variants (265 structural variants included)

Array Content

• Contains 59,795 SNPs selected for high-throughput production arrays based on genome coverage and informativeness for goat species
• Includes SNPs with different MAF profiles, SNPs from diverse breeds, mitochondrial markers, Y markers, and structural variants
• SNPs designed to complement current GBS data and fill genomic gaps

Applications

• Genome-wide association studies (GWAS)
• Molecular breeding: association mapping and genomic selection
• Custom array creation by selecting SNPs from this array (all SNPs validated for performance)

Required Products

• GeneChip Command Console Software
• GeneTitan Multi-Channel Instrument
• Axiom Analysis Suite Software
• Axiom Long Format Export Tool (AxLE)

Specifications