Thermo Fisher Scientific CTRP6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CTRP6. Recombinant protein control fragment (Product #RP-101999). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CTRP6,uniProtId:Q9BXI9-2,ncbiNodeId:9606,antigenRange:56-188,antigenLength:278,antigenImageFileName:PA5-51674_CTRP6_Q9BXI9-2_Rabbit.svg,antigenImageFileNamePDP:PA5-51674_CTRP6_Q9BXI9-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640240

Product Specific Information

Immunogen sequence: CQRCCDSEDP LDPAHVSSAS SSGRPHALPE IRPYINITIL KGDKGDPGPM GLPGYMGREG PQGEPGPQGS KGDKGEMGSP GAPCQKRFFA FSVGRKTALH SGEDFQTLLF ERVFVNLDGC FDMATGQFAA PLR

Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 66%.

Target Information

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP6 contains at least 4 glycosylation motifs, suggesting that CTRP6 may be highly post-translationally modified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.