Thermo Fisher Scientific ABL2 Monoclonal Antibody (5C7)
ABL2 단백질을 표적으로 하는 Mouse IgG3 단클론 항체로, Western blot 및 ELISA에 적합. 고순도 친화 크로마토그래피 정제 제품. PBS 완충액 내 액상 형태로 제공되며 보존제 무첨가. 세포 신호전달 및 종양 연구용으로 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5C7 |
| Immunogen | ABL2 (AAH65912, 743–842 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KKTLGLRAGK PTASDDTSKP FPRSNSTSSM SSGLPEQDRM AMTLPRNCQR SKLQLERTVS TSSQPEENVD RANDMLPKKS EESAAPSRER PKAKLLPRGA
Target Information
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization.
Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to ABL1, including tyrosine kinase, SH2, and SH3 domains, and plays a role in cytoskeletal rearrangements through its C-terminal F-actin and microtubule-binding sequences.
Abl2 is expressed in both normal and tumor cells and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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