Thermo Fisher Scientific SERPINA3 Monoclonal Antibody (1C10)
인간 SERPINA3 단백질을 인식하는 Mouse IgG2a monoclonal antibody. IHC, ICC/IF, ELISA에 사용 가능하며, 높은 특이성과 안정성을 제공. PBS buffer에 보관하며, 연구용으로만 사용.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C10 |
| Immunogen | SERPINA3 (AAH03559, 25 a.a. ~ 423 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PNSPLDEENL TQENQDRGTH VDLGLASANV DFAFSLYKQL VLKAPDKNVI FSPLSISTAL AFLSLGAHNT TLTEILKGLK FNLTETSEAE IHQSFQHLLR TLNQSSDELQ LSMGNAMFVK EQLSLLDRFT EDAKRLYGSE AFATDFQDSA AAKKLINDYV KNGTRGKITD LIKDLDSQTM MVLVNYIFFK AKWEMPFDPQ DTHQSRFYLS KKKWVMVPMM SLHHLTIPYF RDEELSCTVV ELKYTGNASA LFILPDQDKM EEVEAMLLPE TLKRWRDSLE FREIGELYLP KFSISRDYNL NDILLQLGIE EAFTSKADLS GITGARNLAV SQVVHKAVLD VFEEGTEASA ATAVKITLLS ALVETRTIVR FNRPFLMIIV PTDTQNIFFM SKVTNPKQA
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer’s disease (AD) and in normal aged human and monkey brain.
Regulation of serine proteases and their inhibitors plays an important role in neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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