Thermo Fisher Scientific GZMM Monoclonal Antibody (4D11)
GZMM 단백질을 인식하는 Mouse monoclonal antibody(4D11)로 Western blot 및 ELISA에 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 형태. PBS buffer, 무보존제, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D11 |
| Immunogen | GZMM (NP_005308, 85 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of GST tag alone: 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DSPGLTFHIK AAIQHPRYKP VPALENDLAL LQLDGKVKPS RTIRPLALPS KRQVVAAGTR CSMAGWGLTH QGGRLSRVLR ELDLQVLDTR MCNNSRFWNG SLSPSMVCL
Target Information
Cleaves peptide substrates after methionine, leucine, and norleucine.
Physiological substrates include EZR, alpha-tubulins, and the apoptosis inhibitor BIRC5/Survivin.
Promotes caspase activation and subsequent apoptosis of target cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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