Thermo Fisher Scientific MT-ND5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-400 of mouse MT-ND5 (NP_9043381) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MT-ND5,uniProtId:P03921-1,ncbiNodeId:10090,antigenRange:300-400,antigenLength:607,antigenImageFileName:PA5-88563_MT-ND5_P03921-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88563_MT-ND5_P03921-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.89 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804998

Product Specific Information

Immunogen sequence: KIIAFSTSSQ LGLMMVTLGM NQPHLAFLHI CTHAFFKAML FMCSGSIIHS LADEQDIRKM GNITKIMPFT SSCLVIGSLA LTGMPFLTGF YSKDLIIEAI N; Positive Samples: U-251MG, HeLa, Mouse heart, Rat heart; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein

Target Information

A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 5 (ND5) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encoding for ND5 are implicated in Mitochondrial neurogastrointestinal encephalomyopathy, an autosomal recessive multisystem disorder that results in dramatically elevated levels of circulating thymidine and deoxyuridine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.