Thermo Fisher Scientific CD200 Polyclonal Antibody
CD200 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot에 최적화되어 있으며 인간 시료에 반응. 합성 펩타이드로 면역화되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human CD200 (aa 175–224) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608823 |
Product Specific Information
- Peptide sequence: PRSGIENSTV TLSHPNGTTS VTSILHIKDP KNQVGKEVIC QVLHLGTVTD
- Sequence homology:
- Cow: 79%
- Dog: 79%
- Guinea Pig: 79%
- Human: 100%
- Mouse: 79%
- Pig: 86%
- Rabbit: 79%
- Rat: 79%
Target Information
CD200 is a type-1 membrane glycoprotein containing two immunoglobulin domains and belongs to the immunoglobulin superfamily. It is broadly distributed on cell surfaces and interacts with CD200R on myeloid cells to locally prevent macrophage activation. Homologues of CD200 exist in various herpesviruses and poxviruses. Research indicates CD200 may regulate myeloid cell activity and deliver inhibitory signals to macrophage lineages in diverse tissues. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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