Thermo Fisher Scientific SMC2 Monoclonal Antibody (GT4312)
Human SMC2 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. Protein G 정제, PBS 용액 형태로 제공되며 보존제가 포함되어 있지 않습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT4312 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of Human SMC2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735366 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2
- Predicted Reactivity: Mouse (90%), Rat (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are members of the SMC (Structural Maintenance of Chromosome) family that form a heterodimeric complex required for mitotic chromosome condensation, ensuring proper segregation of genetic information during cell division.
The hCAP-C/hCAP-E complex, known as condensin, interacts with phosphorylated Histone H3 to mediate chromosome condensation.
Distinct distribution patterns of the two heterodimeric complexes in the interphase nucleus suggest independent behavior during the cell cycle, indicating their involvement in different aspects of mitotic chromosome organization in human cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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