
Thermo Fisher Scientific TP53I3 Polyclonal Antibody, MaxPab
TP53I3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot에 적합하며, 인간 시료에 반응. PBS 버퍼에 보관되며 방부제 무첨가. p53 매개 세포사멸 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TP53I3 (NP_004872, 1–332 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MLAVHFDKPG GPENLYVKEV AKPSPGEGEV LLKVAASALN RADLMQRQGQ YDPPPGASNI
LGLEASGHVA ELGPGCQGHW KIGDTAMALL PGGGQAQYVT VPEGLLMPIP EGLTLTQAAA
IPEAWLTAFQ LLHLVGNVQA GDYVLIHAGL SGVGTAAIQL TRMAGAIPLV TAGSQKKLQM
AEKLGAAAGF NYKKEDFSEA TLKFTKGAGV NLILDCIGGS YWEKNVNCLA LDGRWVLYGL
MGGGDINGPL FSKLLFKRGS LITSLLRSRD NKYKQMLVNA FTEQILPHFS TEGPQRLLPV
LDRIYPVTEI QEAHKYMEAN KNIGKIVLEL PQTarget Information
The protein encoded by this gene is similar to oxidoreductases, enzymes involved in cellular responses to oxidative stresses and irradiation.
This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death.
It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence.
The microsatellite polymorphism may be associated with differential susceptibility to cancer.
At least two transcript variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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