Thermo Fisher Scientific CD4 Monoclonal Antibody (74-12-4), PE-Cyanine5
돼지 CD4 항원을 인식하는 단클론 항체로, PE-Cyanine5 형광체로 결합되어 유세포분석(Flow Cytometry)에 적합합니다. 고순도 정제 및 안정화 PBS 용액에 보관되며, 4°C 암소 보관 권장. 연구용 전용 제품입니다.
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Applications
- Flow Cytometry (Flow): Tested at 0.2 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 74-12-4 |
| Immunogen | Fresh dd miniature swine thymocytes |
| Conjugate | PE-Cyanine5 |
| Excitation / Emission Max | 568 / 666 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.1, with proprietary stabilizer |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745693 |
Available Formats
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) and may also be found in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression can be detected in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain, gut, and other non-lymphoid tissues. CD4 plays a key role in initiating or augmenting T-cell activation via association with the T-cell receptor complex and the protein tyrosine kinase Lck. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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