Thermo Fisher Scientific GDAP1L1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GDAP1L1. Recombinant protein control fragment (Product #RP-103879). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GDAP1L1,uniProtId:Q96MZ0-1,ncbiNodeId:9606,antigenRange:89-148,antigenLength:367,antigenImageFileName:PA5-64101_GDAP1L1_Q96MZ0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64101_GDAP1L1_Q96MZ0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641934

Product Specific Information

Immunogen sequence: FMRLNLGEEV PVIIHRDNII SDYDQIIDYV ERTFTGEHVV ALMPEVGSLQ HARVLQYREL

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.