
Thermo Fisher Scientific GDAP1L1 Polyclonal Antibody
인간 GDAP1L1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 면역조직화학(IHC) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GDAP1L1. Recombinant protein control fragment (Product #RP-103879) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641934 |
Product Specific Information
Immunogen sequence:
FMRLNLGEEV PVIIHRDNII SDYDQIIDYV ERTFTGEHVV ALMPEVGSLQ HARVLQYREL
Antigen sequence identity:
- Mouse: 97%
- Rat: 97%
Target Information
The ganglioside GD3 synthase induces cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, several genes are upregulated, including one that encodes ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene exists in humans, and mutations in this gene are associated with Charcot-Marie-Tooth type 4A disease. The encoded protein is similar in sequence to human GDAP1, and several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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