Thermo Fisher Scientific BCKDHB Polyclonal Antibody
Human BCKDHB 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BCKDHB (Product #RP-94643) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2638504 |
Product Specific Information
Immunogen sequence:
QVAHFTFQPD PEPREYGQTQ KMNLFQSVTS ALDNSLAKDP TAVIFGEDVA FGGVFRCTVG LRD
Antigen sequence identity:
- Mouse: 90%
- Rat: 92%
Target Information
Branched-chain keto acid dehydrogenase (BCKDH) is a multienzyme complex associated with the inner mitochondrial membrane and is involved in the catabolism of branched-chain amino acids.
The complex consists of multiple copies of three components:
- Branched-chain alpha-keto acid decarboxylase (E1)
- Lipoamide acyltransferase (E2)
- Lipoamide dehydrogenase (E3)
This gene encodes the E1 beta subunit. Mutations in this gene are associated with maple syrup urine disease (MSUD), type 1B, characterized by a maple syrup odor in urine, mental and physical retardation, and feeding difficulties.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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