Thermo Fisher Scientific BCKDHB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human BCKDHB. Recombinant protein control fragment (Product #RP-94643). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BCKDHB,uniProtId:P21953-1,ncbiNodeId:9606,antigenRange:50-112,antigenLength:392,antigenImageFileName:PA5-56785_BCKDHB_P21953-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56785_BCKDHB_P21953-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638504

Product Specific Information

Immunogen sequence: QVAHFTFQPD PEPREYGQTQ KMNLFQSVTS ALDNSLAKDP TAVIFGEDVA FGGVFRCTVG LRD

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 92%.

Target Information

Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria, and functions in the catabolism of branched-chain amino acids. The complex consists of multiple copies of 3 components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). This gene encodes the E1 beta subunit, and mutations therein have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation, and feeding problems.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.