Thermo Fisher Scientific YBX1 Polyclonal Antibody
YBX1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간에 반응하며, sequence homology에 따라 소, 마우스, 랫, 제노푸스에도 예측 반응합니다. 고순도 정제 및 안정적 액상 형태로 제공됩니다.
- 카탈로그번호
- PA513307
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 276–305 amino acids from the C-terminal region of human YBX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Size-exclusion – Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2219267 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, rat, and Xenopus based on sequence homology.
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. It stabilizes cytoplasmic mRNA and modulates translation by influencing interactions with eukaryotic initiation factors. YBX1 also binds to Y-box-containing promoters (5'-CTGATTGGCCAA-3'), such as HLA class II genes, regulating transcription of numerous genes. Additionally, it promotes DNA strand separation, exhibits endonucleolytic activity, and may contribute to DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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