Thermo Fisher Scientific eIF2b epsilon Recombinant Rabbit Monoclonal Antibody (ARC1774)
eIF2b epsilon 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC, ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 인간, 마우스, 랫트 시료에 반응합니다. 단백질 합성 조절 관련 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1774 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human eIF2B epsilon (EIF2B5) (UniProt ID: Q13144) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898092 |
Product Specific Information
- Positive Samples: HeLa, HT-29, U-87MG
- Immunogen sequence:
MAAPVVAPPG VVVSRANKRS GAGPGGSGGG GARGAEEEPP PPLQAVLVAD SFDRRFFPIS KDQPRVLLPL ANVALIDYTL EFLTATGVQE TFVFCCWKAA
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (eIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis.
Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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