Thermo Fisher Scientific RAD23B Polyclonal Antibody
Human RAD23B 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 높은 항원 특이성과 항체 순도를 제공하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로 DNA 손상 복구 관련 단백질 분석에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAD23B. Recombinant protein control fragment (Product #RP-95282). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646279 |
Product Specific Information
Immunogen sequence:
VIEALRASFN NPDRAVEYLL MGIPGDRESQ AVVDPPQAAS TGAPQSSAVA AAAATTTATT TTTSSGGHPL EFLRNQPQFQ QMRQIIQQNP
Highest antigen sequence identity to orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
The RAD23B protein is one of two human homologs of Saccharomyces cerevisiae Rad23, involved in nucleotide excision repair (NER). It forms part of a protein complex that complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts. RAD23B interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair. The protein contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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