Thermo Fisher Scientific RAD23B Polyclonal Antibody
RAD23B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공. 인간 RAD23B 단백질 연구용으로 적합.
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- PA556237
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAD23B. Recombinant protein control fragment (Product #RP-95283). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646280 |
Product Specific Information
Immunogen sequence:
LPALLQQIGR ENPQLLQQIS QHQEHFIQML NEPVQEAGGQ GGGGGGGSGG IAEAGSGHMN YIQVTPQE
Sequence identity (orthologs):
- Mouse: 88%
- Rat: 91%
Target Information
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). It complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro and interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair. The protein contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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