Thermo Fisher Scientific FGL2 Polyclonal Antibody
FGL2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도(>95%) 제품으로 연구용에 적합.
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Thermo Fisher Scientific FGL2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 6–60 of human Fgl2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553501 |
Product Specific Information
- Detects endogenous FGL2 protein at a molecular weight of approximately 50 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and plays a key role in thrombosis-related diseases such as virus-induced fulminant hepatitis, fetal loss syndrome, and xenograft rejection.
Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on T cell proliferation and dendritic cell maturation.
Fgl2 is a serine protease that directly cleaves prothrombin to thrombin, contributing to the pathogenesis of viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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