Thermo Fisher Scientific TRK fused gene Polyclonal Antibody
인간 TFG 단백질을 인식하는 Thermo Fisher의 폴리클로날 항체. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액에 40% 글리세롤 포함, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TFG. Recombinant protein control fragment (Product #RP-92560). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648412 |
Product Specific Information
Immunogen sequence:
PQQLPAQPPQ QYQASNYPAQ TYTAQTSQPT NYTVAPASQP GMAPSQPGAY QPRPGFTSLP GSTMTPPPSG PNPYARNRPP FGQGYTQPG
Sequence identity:
Mouse - 85%, Rat - 85%
Target Information
TFG protein is a human homolog of mouse TFG protein containing an N-terminal coiled-coil structure and SPYGQ-rich region with octicosapeptide repeats. Research indicates TFG modulates SHP-1 activity and is a member of the NF-kB pathway. It associates with proteins such as TANK and NEMO and is implicated in oncogenic rearrangements including TRK-T3 (thyroid), ALK (anaplastic lymphoma), and NOR1 (mixoid chondrosarcoma).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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